A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 33/06 (2006.01) A61K 47/10 (2006.01)
Patent
CA 2651329
The invention provides compositions, kits, and methods for treatment of neuronal injury. In one embodiment, the composition comprises a biomembrane sealing agent, such as PEG, and a bioactive agent, such as a magnesium compound. The biomembrane sealing agent and/or the bioactive agent may be delivered by a method selected from the group consisting of an intravenous administration, an intramuscular administration, an intrathecal administration, a subcutaneous administration, an epidural administration, a parenteral administration, a direct application onto or adjacent to a site of the pathological condition, and any combinations thereof. Alternatively, the biomembrane sealing agent and/or the bioactive agent may be delivered from a pump or an implant.
L'invention concerne des compositions, des trousses, et des méthodes destinées au traitement de traumatisme crânien. Dans un mode de réalisation, la composition comprend un agent d'obturation de biomembrane, par ex. PEG, et un agent bioactif, par ex. un composé de magnésium. L'agent d'obturation de biomembrane et/ou l'agent bioactif peuvent être acheminés indépendamment par le biais d'une administration intraveineuse, intramusculaire, intrathécale, sous-cutanée, épidurale, parentérale ou directe sur ou encore à proximité d'un site de l'état pathologique et par le biais de quelconques combinaisons de ces administrations. Dans une autre variante, l'agent d'obturation de biomembrane et/ou l'agent bioactif peuvent être administrés à partir d'une pompe ou d'un implant.
Marx Jeffery C.
Mckay William F.
Roy Josee
Smart & Biggar
Warsaw Orthopedic Inc.
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