Compositions comprising cyclohexylamines and aminoadamantanes

Details Compositions comprising cyclohexylamines and aminoadamantanes Compositions comprising cyclohexylamines and aminoadamantanes

A - Human Necessities

61

K

A61K 9/08 (2006.01)

Patent

CA 2543865

The invention is directed to formulations of pharmaceutical compounds, such as the Cyclohexylamines and Aminoadamantanes which have antimicrobial properties. In particular, it is directed to aqueous based formulations with reduced amounts of preservatives which allow safe and convenient administration and flexible dosing and which, in the case of oral formulations, are easy to swallow. Optionally, the compositions contain components that provide the requisite stability and shelf life while reducing or avoiding incrustation of the composition around the container closure which leads to leaks and difficulty in opening the container.

L'invention concerne des formulations de composés pharmaceutiques, tels que les cyclohexylamines et les aminoadamantanes qui possèdent des propriétés antimicrobiennes. Plus particulièrement, l'invention concerne des formulations aqueuses dont la faible concentration en agents de conservation rend leur administration pratique et sans danger et permet une posologie souple; dans le cas de formulations orales, celles-ci sont faciles à avaler. Dans une variante, ces compositions contiennent des composants qui leur confèrent la stabilité et la durée de conservation requises, tout en réduisant ou empêchant le dépôt de la composition autour du système de fermeture du récipient qui est à l'origine de fuites et de difficultés d'ouverture du récipient.

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