Compositions comprising dendrimer complexes

A - Human Necessities – 61 – K

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Details

A61K 47/48 (2006.01) A61K 41/00 (2006.01) A61K 47/30 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2408535

The present invention relates to novel therapeutic and diagnostic arrays. More particularly, the present invention is directed to dendrimer based multifuntional compositions and systems for use in disease diagnosis and therapy (e.g., cancer diagnosis and therapy). The compositions and systems generally comprise two or more separate components for targeting, imaging, sensing, and/or triggering release of a therapeutic or diagnostic material and monitoring the response to therapy of a cell or tissue (e.g., a tumor).

La présente invention concerne de nouveaux systèmes thérapeutiques et diagnostiques. La présente invention concerne, en particulier, des compositions et des systèmes multifonction à base de dendrimères, destinés à être utilisés dans le cadre du diagnostic et du traitement de maladies (par exemple, le diagnostic et la traitement du cancer). Lesdites compositions et lesdits systèmes comprennent au moins deux composants séparés servant à cibler, à imager, détecter et/ ou à déclencher la libération d'une substance thérapeutique ou diagnostique et à surveiller la réponse thérapeutique d'une cellule ou d'un tissu (par exemple, une tumeur).

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