C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/435 (2006.01) A61K 35/64 (2006.01) A61K 39/39 (2006.01)
Patent
CA 2543072
The present invention provides novel adjuvant systems that reduce the risk of toxic side effects associated with the use of known adjuvants while providing powerful stimulation of immune responses against target antigens. These novel adjuvant systems are based on the honey bee venom melittin or specific cationic peptides derived from melittin and ae capable of eliciting strong immune responses against target antigens. To further enhance their immunogenicity they can be optionally combined with synthetic oligonucleotides (ODNs) lacking any immunostimulatory sequences such as CpG motifs.
La présente invention concerne un peptide immunostimulateur, une composition immunostimulatrice contenant ledit peptide et l'utilisation de ladite composition pour la fabrication d'un produit pharmaceutique.
Blake Cassels & Graydon Llp
Intercell Ag
Pevion Biotech Ltd.
LandOfFree
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