Compositions comprising mixtures of therapeutic proteins and...

Details Compositions comprising mixtures of therapeutic proteins and... Compositions comprising mixtures of therapeutic proteins and...

A - Human Necessities

61

K

A61K 38/19 (2006.01) A61K 38/20 (2006.01) A61K 38/21 (2006.01) C07K 14/52 (2006.01) C07K 14/525 (2006.01) C07K 14/53 (2006.01) C07K 14/535 (2006.01) C07K 14/54 (2006.01) C07K 14/545 (2006.01) C12P 21/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2459307

Human cytokine mixtures produced by cytokine regulatory factor-overexpressing cells and methods of production are disclosed. The mixtures are prepared by culturing human cytokine-producing cells under conditions of cytokine regulatory factor overexpression, treating the cells to induce cytokine production, and isolating the mixtures of cytokines produced by the cells. Preferred compositions, for use in treating viral infection or cancer, include a mixture of human interferon .gamma. and either human interferon .alpha. or human interferon .beta., in a mole ratio of between 1:1 to 1:100 interferon .gamma. to interferon .alpha. or human interferon .beta..

L'invention concerne des mélanges de cytokines humaines produits au moyen de cellules surexprimant le facteur de régulation des cytokines, ainsi que leurs procédés de préparation. Ces mélanges sont préparés par culture de cellules productrices de cytokines humaines dans des conditions de surexpression du facteur de régulation des cytokines, par traitement des cellules en vue d'induire une production de cytokines, puis par isolement des mélanges de cytokines produites par ces cellules. Utilisées dans le traitement de l'infection virale ou du cancer, les compositions préférées comprennent un mélange d'interféron humain .gamma. et d'interféron humain .alpha. ou d'interféron humain .beta. dans un rapport molaire de 1:1 à 1:100 entre l'interféron .gamma. et l'interféron .alpha. ou l'interféron .beta..

Affiliated with

Also associated with

Rating

Compositions comprising mixtures of therapeutic proteins and... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compositions comprising mixtures of therapeutic proteins and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions comprising mixtures of therapeutic proteins and... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1487756