Compositions comprising modafinil for treatment of attention...

A - Human Necessities – 61 – K

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A61K 31/165 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2380673

Modafinil is effective in improving symptoms of attention deficit hyperactivity disorder and symptoms of multiple sclerosis fatigue. The administration of modafinil is also shown to activate the tuberomamillary neurons of the posterior hypothala-mus, and thus exhibits activity in an area of the brain associated with normal wakefulness functions.

Le modafinil permet de lutter efficacement contre les symptômes du trouble déficitaire de l'attention et les symptômes de la fatigue ressentie par les patients atteints de sclérose en plaques. Il a également été démontré que l'administration du modafinil active les neurones tubéro-mamillaires de l'hypothalamus postérieur, et développe ainsi une activité dans une zone du cerveau associée aux fonctions de veille normales.

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