Compositions comprising modified lcat and use thereof for...

Details Compositions comprising modified lcat and use thereof for... Compositions comprising modified lcat and use thereof for...

A - Human Necessities

61

K

A61K 31/497 (2006.01) A61P 3/00 (2006.01) A61P 3/06 (2006.01) A61P 9/10 (2006.01) A61P 9/12 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2654661

The invention provides compounds, pharmaceutical compositions and methods for treating atherosclerosis, inflammation, thrombosis and other conditions and for decreasing or prevention of accumulation of cholesterol in a subject by modifying LCAT polypeptide.

L'invention concerne des composés, des compositions pharmaceutiques et des procédés destinés au traitement de l'athérosclérose, de l'inflammation, de la thrombose et d'autres états, qui permettent de réduire ou prévenir l'accumulation de cholestérol chez un sujet en modifiant le polypeptide LCAT.

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