Compositions comprising organic extracts of geum japonicum...

A - Human Necessities – 61 – K

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A61K 36/73 (2006.01) A61P 9/00 (2006.01) A61P 9/10 (2006.01) A61P 17/02 (2006.01) A61P 19/08 (2006.01)

Patent

CA 2467895

The invention provides an organic extract of Geum Japonicum thunb var. (EGJ), and a pharmaceutical composition comprising the same. The organic EGJ has been identified to show potent dual effects on stimulating early growth (less than 48 hours) of new vessels both in ischemic heart muscles and in infracted heart muscles, and on triggering myocardial regeneration in myocardial infarction, and therefore, may be used in the treatment of ischemic diseases in human being or animals including ischemic heart disease and ischemic limbs, and damaged myocardium associated diseases.

L'invention concerne un extrait organique de Geum Japonicum thunb var. (EGJ), ainsi qu'une composition pharmaceutique contenant cet extrait. L'EGJ organique a montré qu'il avait un double effet puissant stimulant, d'une part, la croissance précoce (moins de 48 heures) de nouveaux vaisseaux à la fois dans des muscles cardiaques présentant une ischémie et dans des muscles cardiaques ayant subi un infarctus, et déclenchant, d'autre part, la régénération du myocarde en cas d'infarctus du myocarde. L'EGJ organique peut donc être utilisé dans le traitement de maladies ischémiques chez l'homme et les animaux, y compris la cardiopathie ischémique et l'ischémie des membres, ainsi que des maladies associées à l'endommagement du myocarde.

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