Compositions comprising pde4 modulators and their use for...

A - Human Necessities – 61 – K

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A61K 31/00 (2006.01) A61K 31/403 (2006.01) A61K 31/4035 (2006.01) A61K 31/4245 (2006.01) A61K 45/06 (2006.01) A61P 11/00 (2006.01)

Patent

CA 2590903

Methods of treating, preventing, and managing airway inflammation and other airway or pulmonary diseases and disorders are disclosed. Specific methods comprise the administration of a PDE4 modulator, or a pharmaceutically acceptable salt, solvate, stereoisomer, or prodrug thereof, alone or in combination with a second active agent and/or other conventional therapies. Pharmaceutical compositions, single unit dosage forms, and kits suitable for use in methods of the invention are also disclosed.

La présente invention décrit des méthodes de traitement, de prévention et de soulagement d'une inflammation des voies respiratoires et d'autres maladies ou troubles des voies respiratoires ou des poumons. Plus précisément, les méthodes comprennent l'administration d'un modulateur de l'activité de PDE4, ou d'un sel, d'un solvate, d'un stéréoisomère, ou d~une prodrogue de qualité pharmaceutique dudit modulateur, seul ou combiné à un second principe actif et/ou à d'autres thérapies conventionnelles. La présente invention décrit en outre des préparations pharmaceutiques, des formes galéniques sous forme de doses unitaires, et des kits pouvant être employés dans les méthodes de l'invention.

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