Compositions comprising phenylephrine and acetaminophen for...

Details Compositions comprising phenylephrine and acetaminophen for... Compositions comprising phenylephrine and acetaminophen for...

A - Human Necessities

61

K

A61K 31/137 (2006.01) A61K 31/167 (2006.01) A61K 31/485 (2006.01) A61K 47/10 (2006.01) A61K 47/12 (2006.01) A61K 47/20 (2006.01) A61P 11/02 (2006.01) A61P 11/04 (2006.01) A61P 11/10 (2006.01)

Patent

CA 2649997

Disclosed are compositions including phenylephrine, its salts, and mixtures thereof, in combination with acetaminophen; and optionally in combination with additional pharmaceutical actives. The compositions have a pH of about 6.5 to about 7.5 and may be substantially free of aldehydes. The invention also provides a method of stabilizing phenylephrine. Also disclosed are methods of treating respiratory illness through administration of a composition comprising phenylephrine, its salts, and mixtures thereof, in combination with acteaminophen; and optionally in combination with additional pharmaceutical actives, wherein the composition has a pH of from about 6.5 to about 7.5 and may be substantially free of aldehydes.

L'invention concerne des compositions comprenant de la phényléphrine, des sels de celle-ci et des mélanges de ceux-ci, en association avec du paracétamol; et éventuellement en association avec des ingrédients pharmaceutiques actifs supplémentaires. Les compositions ont un pH d'environ 6,5 à environ 7,5 et peuvent être sensiblement exemptes d'aldéhydes. L'invention concerne également un procédé de stabilisation de la phényléphrine. L'invention concerne également des procédés de traitement d'une maladie respiratoire grâce à l'administration d'une composition comprenant de la phényléphrine, des sels de celle-ci et des mélanges de ceux-ci, en association avec du paracétamol; et éventuellement en association avec des ingrédients pharmaceutiques actifs supplémentaires, ladite composition ayant un pH allant d'environ 6,5 à environ 7,5 et pouvant être sensiblement exempte d'aldéhydes.

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