Compositions comprising pneumococcal antigens

Details Compositions comprising pneumococcal antigens Compositions comprising pneumococcal antigens

A - Human Necessities

61

K

A61K 39/09 (2006.01) C07K 14/315 (2006.01) C07K 19/00 (2006.01) C12N 1/21 (2006.01)

Patent

CA 2695169

The inventors believe that an effective Streptococcus pneumoniae vaccine may require several antigenic components, and so they have identified various combinations of pneumococcal polypeptides for use in immunisation. They have also identified some pneumococcal polypeptides that may be useful as single antigens. These polypeptides may optionally be used in combination with pneumococcal saccharides. The antigens may be used in pneumococcal vaccines, but may also be used as components in vaccines for immunising against multiple pathogens.

Selon les inventeurs, pour obtenir un vaccin efficace contre Streptococcus pneumoniae, on doit recourir à plusieurs composants antigéniques. Ainsi, ils ont identifiés des combinaisons variées de polypetides servant à l'immunisation. Ils ont également identifiés certains polypetides pneumococciques pouvant servir d'antigènes uniques. Les polypeptides de l'invention peuvent éventuellement être utilisés combinés à des saccharides pneumococciques. Les antigènes de l'invention peuvent être utilisés dans des vaccins pneumococciques ou peuvent servir de composants dans des vaccins immunisant contre plusieurs pathogènes.

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