A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/728 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2634053
The present invention relates to compositions comprising polycation-complexed protein crystals and hyaluronic acid. Advantageously, the compositions of this invention are stable, long- acting and avoid local reactions at the injection site. Compositions according to this invention include sustained-release human growth hormone compositions. Such compositions are useful for treating a subject having a disorder associated with human growth hormone deficiency or that is ameliorated by human growth hormone therapy.
L'invention concerne des compositions comprenant des cristaux de protéines complexes par des polycations et de l'acide hyaluronique. De manière avantageuse, les compositions de l'invention sont stables, à action prolongée et permettent d'éviter des réactions locales sur le site d'injection. Les compositions de l'invention comprennent des compositions, comportant l'hormone de croissance humaine, à libération prolongée. Lesdites compositions sont utilisées pour traiter un sujet présentant un trouble associé à une insuffisance en hormone de croissance humaine ou à un trouble qui peut être amélioré par une thérapie comprenant l'utilisation de l'hormone de croissance humaine.
Basu Sujit Kumar
Mishra Shubhang
Qu Susan Yun
Simeone Benjamin Paul
Althea Technologies Inc.
Altus Pharmaceuticals Inc.
Smart & Biggar
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