A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/382 (2006.01) A61K 9/22 (2006.01) A61K 31/195 (2006.01) A61K 31/385 (2006.01) A61K 31/41 (2006.01) A61K 31/4178 (2006.01) A61K 31/4184 (2006.01) A61P 3/10 (2006.01) A61P 9/12 (2006.01)
Patent
CA 2745383
Compositions are provided which can be useful in treating a renin-angiotensin aldosterone system-related disorder. These compositions include renin-angiotensin aldosterone system inhibitors and lipoic acid compounds, as well as other therapeutic agents, and are useful in treating hypertension, stroke, metabolic syndrome, or other renin-angiotensin al-dosterone system-related disorders in a subject. The compositions are also useful in improving vasodilation, reducing proteinuria, and reducing insulin resistance in a subject. Pharmaceutical compositions and methods of treatment using the compositions are further provided.
L'invention concerne des compositions pouvant être utiles dans le traitement d'un trouble associé au système rénine-angiotensine-aldostérone. Ces compositions contiennent des inhibiteurs du système rénine-angiotensine-aldostérone et des composés de l'acide lipoïque, ainsi que d'autres agents thérapeutiques, et sont utiles pour traiter l'hypertension, les attaques, le syndrome métabolique et d'autres troubles associés au système rénine-angiotensine-aldostérone chez un sujet. Les compositions sont également utiles pour améliorer la vasodilatation, réduire la protéinurie et diminuer la résistance à l'insuline chez un sujet. Des compositions pharmaceutiques et des procédés de traitement utilisant les compositions sont également décrits.
Khan Bobby V.
Parthasarathy Sam
In Vasc Therapeutics Inc.
Moffat & Co.
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