Compositions comprising salmonella porins and uses thereof...

Details Compositions comprising salmonella porins and uses thereof... Compositions comprising salmonella porins and uses thereof...

A - Human Necessities

61

K

A61K 39/39 (2006.01) A61K 39/112 (2006.01) A61K 39/145 (2006.01) A61K 39/295 (2006.01) A61P 31/16 (2006.01) A61P 37/04 (2006.01)

Patent

CA 2728374

Adjuvants comprising OmpC porin, OmpF porin, or a combination thereof, are provided. The adjuvants can be administered to a subject in combination with antigenic material in order to potentiate the immunogenic effect of the antigenic material. Also provided are products comprising antigenic material in combination with OmpC and/or OmpF, including products comprising a pre-formulated vaccine in combination with OmpC and/or OmpF. Further provided is the use of OmpC and/or OmpF to improve the effect of a pre-formulated vaccine.

Cette invention concerne des adjuvants comprenant une porine OmbC, une porine OmpF ou une combinaison des deux. Ces adjuvants peuvent être administrés à un sujet en association avec un matériau antigénique dans le but de potentialiser l'effet immunogénique de matériau antigénique. L'invention concerne également des produits contenant le matériau antigénique en combinaison avec OmpC et/ou OmpF, dont des produits contenant un vaccin préformulé en association avec OmpC et/ou OmpF. L'invention concerne en outre des produits contenant un vaccin préformulé en association avec OmpC et/ou OmpF. Enfin, l'invention concerne l'utilisation de OmpC et/ou de OmpF dans le but d'améliorer l'effet du vaccin préformulé

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