Compositions comprising tetrahydrothienopyridine derivatives...

A - Human Necessities – 61 – K

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A61K 31/44 (2006.01) A61K 31/535 (2006.01)

Patent

CA 2061173

Compositions comprising tetrahydrothianopyridine derivatives as angiogenesis inhibitors ABSTRACT The invention relates to pharmaceutical compo- sitions comprising compounds of the formula Image in which p is 2 and q is 1 or p is 1 and g is 2; Ar represents an optionally substituted phenyl, and Z represents NR1R2 in which R1 and R2, which may be identical or different, represent H or optionally sub- stituted alkyl or, with the nitrogen atom, form a satu- rated heterocycle, or Z represents OR in which R is H or optionally substituted alkyl, or their salts, in the form of pure enantiomer or of mixtures thereof, for preventing or treating pathologies involving or dependent upon a neovascularisation.

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