Compositions comprising vascular and myocyte progenitor...

A - Human Necessities – 61 – K

Patent

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A61K 35/34 (2006.01) A61P 9/00 (2006.01)

Patent

CA 2743698

The invention provides compositions of adult cardiac vascular progenitor cells (VPCs) and adult cardiac myocyte progenitor cells (MPCs) useful for the treatment of various cardiac conditions. The invention also encompasses methods of generating a biological bypass, repairing damaged myocardium, and treating or preventing hypertensive cardiomyopathy and heart failure with the compositions of the invention. Methods of isolating the cardiac progenitor cells are also disclosed.

Cette invention concerne des compositions et cellules progénitrices vasculaires cardiaques adultes (VPC) et des cellules progénitrices myocytaires cardiaques adultes (MPC) utilisées pour le traitement de diverses affections cardiaques. Cette invention concerne également des procédés permettant de réaliser un biopontage, de réparer un myocarde endommagé et de traiter et de prévenir une myocardiopathie hypertensive et une insuffisance cardiaque avec les compositions décrites dans cette invention. L'invention concerne également des procédés permettant d'isoler les cellules progénitrices cardiaques.

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