C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 7/00 (2006.01) A61K 35/76 (2006.01) A61K 48/00 (2006.01) C12N 7/02 (2006.01) C12N 15/861 (2006.01)
Patent
CA 2320419
A composition is disclosed comprising virus in a formulation comprising a polyhydroxy hydrocarbon buffered to maintain a pH in a range from about 7 to about 8.5 at a temperature in the range from about 2 °C to 27 °C. Methods for concentrating and purifying virus preparations are also disclosed.
L'invention porte sur une composition comprenant un virus dans une formulation renfermant un hydrocarbure polyhydroxy tamponné de façon à maintenir un pH dans une plage comprise entre environ 7 et environ 8,5, à une température comprise entre environ 2 ·C et 27 ·C. L'invention porte également sur des procédés de concentration et de purification de préparations de virus.
Bondoc Laureano L. Jr.
Frei Andreas
Ihnat Peter
Kwan Henry K.
Porter Frederick William IV
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Schering Corporation
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