Compositions containing ansamycin

Details Compositions containing ansamycin Compositions containing ansamycin

A - Human Necessities

61

K

A61K 31/395 (2006.01)

Patent

CA 2631680

Provided are pharmaceutical compositions containing an oil phase and an aqueous phase, the oil phase including an ansamycin and less than 2% w/w oleic acid, wherein the ansamycin is geldanamycin, 17-aminogeldanamycin, lT- allyalamino-lT-demethoxy-geldanamycin, compound (563), or compound (237) having the structures below, or a salt of any one of the aforementioned ansamycins

La présente invention a trait à des compositions pharmaceutiques contenant une phase huileuse et une phase aqueuse, la phase huileuse comprenant une ansamycine et une quantité inférieure à 2 % en poids d'acide oléique, ladite ansamycine étant de la geldanamycine, 17-aminogeldanamycine, 17-allyalamino-17-deméthoxy-geldanamycine, composé 563, ou composé 237 de structures (A et B), ou un sel d'une quelconque parmi les ansamycines susmentionnées.

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