Compositions containing delta-9-thc-amino acid esters and...

A - Human Necessities – 61 – K

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Details

A61K 31/352 (2006.01) A61P 29/00 (2006.01) A61P 31/18 (2006.01) C07D 311/80 (2006.01)

Patent

CA 2741862

Compositions of the formulae (I), (II) and (III); where R1, R2 and R3 are residues of amino acids such as, but not limited to, valine, sarcosine, leucine, glutamine, tryptophan, tyrosine, alanine and 4(4-aminophenyl)butyric acid or combination thereof, and salts thereof. Methods of preparation of these compositions and methods of treating any disease condition responsive to THC comprising administration of at least one these compositions in a pharmaceutically acceptable carrier using a pharmaceutically acceptable formulation.

Cette invention décrit des compositions de formules (I), (II) et (III). Dans ces formules, R1, R2 et R3 sont des résidus d'acides aminés comprenant, entre autres, des résidus valine, sarcosine, leucine, glutamine, tryptophane, tyrosine, alanine et acide 4-(4-aminophényl)butyrique ou une combinaison de ceux-ci, et leurs sels. Des procédés de préparation de ces compositions et des méthodes destinées à traiter toute pathologie réagissant au THC consistant à administrer au moins une de ces compositions dans un véhicule pharmaceutiquement acceptable au moyen d'une formulation pharmaceutiquement acceptable sont également décrits.

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