Compositions containing difluprednate

Details Compositions containing difluprednate Compositions containing difluprednate

A - Human Necessities

61

K

A61K 31/57 (2006.01) A61K 9/00 (2006.01) A61K 9/107 (2006.01)

Patent

CA 2237503

The present invention relates to a liquid composition comprising difluprednate, oil, water and an emulsifier. The composition of the present invention has superior antiinflammatory action and antiallergic action. The composition of the present invention shows superior transfer to a lesion and uniform drug distribution upon administration, as compared to conventional preparations containing difluprednate, so that it shows sufficient efficacy in asmaller dose. The inventive composition is associated with extremely less uncomfortable feeling and foreign sensation upon administration, as compared to conventional preparations containing difluprednate, and it can be administered easily to local sites of eye, nose, ear and the like.

Cette invention porte sur une composition liquide contenant du difluprednate, de l'huile, de l'eau et un émulsifiant. La composition en question possède un effet anti-inflammatoire et un effet antiallergique supérieurs. Cette composition est dotée d'une capacité supérieure de transfert à une lésion et permet une distribution uniforme du médicament à l'administration, comparativement à des préparations conventionnelles contenant du difluprednate, ce qui lui confère une efficacité suffisante même à faible dose. Cette invention est associée à une sensation d'inconfort et de corps étranger beaucoup moins prononcée à l'administration, comparativement à des préparations classiques contenant du difluprednate, et elle peut être administrée facilement à des sites précis, comme les yeux, le nez, les oreilles et autres sites semblables.

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