A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/663 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01) A61K 31/66 (2006.01)
Patent
CA 2346662
The invention relates to a solid pharmaceutical form of administration containing a diphosphonic acid or a physiologically compatible salt thereof as the active substance, wherein the active substance is present in granulate form, optionally together with pharmaceutical adjuvants, in the inner phase and the outer phase contains a lubricant in the form of less than 5% by weight of stearic acid relative to the total weight of the form of administration.
L'invention concerne une forme d'administration pharmaceutique solide contenant un acide diphosphonique ou un sel physiologiquement compatible de celui-ci en tant que substance active, dans laquelle la substance active se présente sous une forme granulaire, facultativement avec des adjuvants pharmaceutiques, et contient dans la phase intérieure et la phase extérieure un lubrifiant sous la forme de moins de 5 % en poids d'un acide stéarique par rapport au poids total de la forme d'administration.
Gabel Rolf-Dieter
Preis Walter
Woog Heinrich
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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