A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/40 (2006.01) A61K 41/00 (2006.01)
Patent
CA 2075895
A method to prepare bone marrow or other hemopoietic cells free of malignant cells for autologous transplants is described The mononuclear cells from the marrow are treated with a green porphyrin (Gp) to effect the uptake of said Gp by malignant cells, selectively, and then irradiated with a wavelength of tight absorbed by said Gp to effect the destruction of the malignant cells. The purged marrow cells can then be used for autologous transplantation.
Méthode de préparation des cellules médullaires ou d'autres cellules hémopoïétiques ne contenant pas de cellules malignes en vue de transplantations autologues. Les cellules médullaires mononucléaires sont traitées avec une porphyrine verte (Gp) afin d'améliorer l'absorption sélective de ladite Gp par les cellules malignes, puis irradiées par une onde de lumière absorbée par ladite Gp afin de détruire ces cellules malignes. Les cellules médullaires ainsi purgées peuvent alors être utilisées pour transplantation autologue.
Jamieson Catriona
Levy Julia G.
Battison Williams Dupuis
The University Of British Columbia
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