Compositions containing, methods involving, and uses of...

C - Chemistry – Metallurgy – 07 – K

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07K 1/02 (2006.01)

Patent

CA 2590590

Disclosed herein are non-natural amino acids and polypeptides that include at least one non-natural amino acid, and methods for making such non-natural amino acids and polypeptides. The non-natural amino acids, by themselves or as a part of a polypeptide, can include a wide range of possible functionalities, but typical have at least one oxime, carbonyl, dicarbonyl, and/or hydroxylamine group. Also disclosed herein are non-natural amino acid polypeptides that are further modified post-translationally, methods for effecting such modifications, and methods for purifying such polypeptides. Typically, the modified non-natural amino acid polypeptides include at least one oxime, carbonyl, dicarbonyl, and/or hydroxylamine group. Further disclosed are methods for using such non-natural amino acid polypeptides and modified non-natural amino acid polypeptides, including therapeutic, diagnostic, and other biotechnology uses.

L'invention concerne des acides aminés non naturels, des polypeptides comportant au moins un acide aminé non naturel, et des procédés pour produire des acides aminés non naturels et des polypeptides. Qu'ils soient employés seuls ou fassent partie d'un polypeptide, les acides aminés non naturels peuvent présenter un large éventail de fonctionnalités possibles, mais comportent généralement un groupe oxime, carbonyle, dicarbonyle, et/ou hydroxylamine. Cette invention concerne également des polypeptides comportant au moins un acide aminé non naturel qui sont encore transformés après l'étape de traduction, des procédés pour mettre ces modifications en oeuvre, ainsi que des procédés pour purifier les polypeptides. Généralement, les polypeptides modifiés comprenant au moins un acide aminé non naturel comportent au moins un groupe oxime, carbonyle, dicarbonyle, et/ou hydroxylamine. Cette invention se rapporte en outre à des procédés pour utiliser lesdits polypeptides modifiés comportant au moins un acide aminé non naturel ainsi que les polypeptides modifiés comportant au moins un acide aminé naturel, procédés parmi lesquels figurent des procédés d'utilisation thérapeutique, diagnostique, et d'autres procédés d'utilisation biotechnologique.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Compositions containing, methods involving, and uses of... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compositions containing, methods involving, and uses of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions containing, methods involving, and uses of... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1665480

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.