Compositions containing peptide copper complexes and...

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/05 (2006.01) A61K 35/60 (2006.01) A61K 38/06 (2006.01) A61K 38/17 (2006.01) A61K 38/29 (2006.01) A61K 38/39 (2006.01) A61K 38/55 (2006.01) A61K 38/57 (2006.01) A61K 45/06 (2006.01) A61P 17/02 (2006.01) A61P 17/14 (2006.01)

Patent

CA 2505523

Novel compositions capable of inhibiting the degradation of extracellular matrices of warm-blooded animals, including humans, and promoting the production of proteins thereof, combine at least one metalloproteinase inhibitor, which may be a matrix metalloproteinase inhibitor, and at least one peptide copper complex. Also disclosed are methods that utilize the disclosed compositions, by administering to warm-blooded animals effective amounts thereof orally, parenterally, or topically, for treating arthritis and other inflammatory conditions, enhancing wound and bone healing, treating skin diseases, treating cosmetic defects of the skin, or stimulating hair growth.

L'invention concerne de nouvelles compositions pouvant inhiber la dégradation de matrices extracellulaires chez les animaux à sang chaud, y compris les humains, et stimuler chez eux la production de protéines. Ces compositions associent au moins un inhibiteur de métalloprotéinase, qui peut être un inhibiteur de métalloprotéinase matricielle, et au moins un complexe de cuivre-peptide. L'invention concerne également des méthodes utilisées pour administrer à des animaux à sang chaud, par voie orale, parentérale ou topique, des quantités efficaces des compositions de l'invention pour traiter l'arthrite et autres affections inflammatoires, accélérer la guérison des plaies ou des os, traiter les dermatoses, traiter les affections apparentes de la peau, ou stimuler la croissance capillaire.

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