Compositions containing plant-produced glycopolypeptide...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/13 (2006.01) A01H 5/00 (2006.01) A61K 39/395 (2006.01) C07K 16/00 (2006.01) C07K 16/12 (2006.01) C07K 16/18 (2006.01) C07K 16/44 (2006.01) C07K 19/00 (2006.01) C12N 9/00 (2006.01) C12N 9/18 (2006.01) C12N 15/52 (2006.01) C12N 15/82 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2071502

2071502 9106320 PCTABS00005 The present invention contemplates a transgenic plant having somatic and germ cells containing at least two mammalian genes coding for polypeptides capable of autogenously associating with each other to form a biologically active multimer. The present invention also contemplates glycopolypeptide multimers having a polypeptide that contains an immunoglobulin amino acid residue sequence and an oligosaccharide that comprises a core pentasaccharide and N-acetylglucosamine-containing outer branches, such that the multimer is free from sialic acid. The production of passive immunity against a preselected antigen by administering a sialic acid free glycopolypeptide multimer to an animal is also comtemplated.

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