Compositions containing platinum

C - Chemistry – Metallurgy – 07 – F

Patent

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260/429.4

C07F 15/00 (2006.01)

Patent

CA 1117544

JMB 654/A ABSTRACT This invention relates to new platinum co-ordination compounds, to pharmaceutical compositions containing them and to their use in the treatment of malignant tumours or malignant neoplasms. In particular a compound according to the present invention comprises a co-ordination compound of platinum having the structure:- Image in which X and Y are halogenoid groups which are the same or different and are preferably both chloride but may be other halide or pseudohalide such as cyanate, thiocyanate and azide, the Z groups are the same and are either hydroxy or halogenoid, preferably chloride, and A and B are the same or different alicyclic amine groups co-ordinated to the Pt through their N atoms.

313745

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