A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/48 (2006.01) A61K 38/36 (2006.01) A61K 38/39 (2006.01) A61L 24/04 (2006.01) A61L 24/10 (2006.01)
Patent
CA 2295247
The present invention relates to thrombin-containing hemostatic compositions, their preparation and use. In particular, it relates to hemostatic compositions comprising stabilized thrombin and microfibrillar collagen in an aqueous medium. In a preferred embodiment of the present invention, the compositions are used in a kit comprising two different components, one of which is autologous patient's plasma as the source of fibrinogen, and the other of which is the thrombin-containing composition which also contains microfibrillar collagen.
Cette invention concerne des compositions hémostatiques contenant de la thrombine, leur préparation et leurs utilisations. De manière plus spécifique cette invention concerne des compositions hémostatiques contenant de la thrombine et du collagène microfibrillaire stabilisés dans un milieu aqueux. Dans une forme de réalisation préférée de l'invention, les compositions sont utilisées dans un kit formé de deux constituants différents, dont un est le plasma autologue du patient qui sert de source de fibrinogène et l'autre est la composition contenant de la thrombine qui contient également du collagène microfibrillaire.
Delustro Frank A.
Prior Jeffrey J.
Sierra David H.
Wallace Donald G.
Angiotech Pharmaceuticals (us) Inc.
Borden Ladner Gervais Llp
Cohesion Technologies Inc.
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