Compositions controlling release ph range and/or speed

Details Compositions controlling release ph range and/or speed Compositions controlling release ph range and/or speed

A - Human Necessities

61

K

A61K 31/5517 (2006.01) A61K 9/14 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 47/30 (2006.01) A61P 1/04 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2412776

The present invention provides a composition controlling a pH range of release and/or a release rate, which contains (i) a thienotriazolodiazepine compound of the formula (I) (see formula I) and (ii) at least one kind of ingredient selected from the group consisting of a water-soluble polymer, an enteric polymer, a water-insoluble polymer and a porous macromolecule and/or a surfactant, as well as a production method thereof.

L'invention concerne des compositions permettant de réguler la plage et/ou la vitesse de libération du pH, qui renferment (i) des composés de thiénotriazolodiazépine représentés par la formule générale (I) ci-après : , (ii) au moins une base sélectionnée dans le groupe constitué des polymères hydrosolubles, des polymères entériques, des polymères hydrosolubles et des polymère poreux ; et/ou un tensioactif ; ainsi qu'un procédé de production desdites compositions.

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