Compositions for continuous administration of dopa...

A - Human Necessities – 61 – K

Patent

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A61K 9/08 (2006.01) A61K 9/10 (2006.01) A61K 31/198 (2006.01) A61P 25/16 (2006.01)

Patent

CA 2761624

Disclosed herein are arginine salts of carbidopa and levodopa and compositions that include for example the arginine salt of carbidopa suitable for continuous administration for treating neurological or movement diseases or disorders such as restless leg syndrome, Parkinson's disease, secondary parkinsonism, Huntington's disease, Parkinson's-like syndrome, PSP, MSA, ALS, Shy-Drager syndrome and conditions resulting from brain injury including carbon monoxide or manganese intoxication, together with administration of levodopa

L'invention concerne des sels d'arginine de carbidopa et de lévodopa et des compositions qui comprennent, par exemple, les sels d'argiline de carbidopa qui sont appropriés pour administrer de manière continue, conjointement avec le lévodopa, un traitement des maladies neurologiques ou des troubles du mouvement, tels que le syndrome des jambes sans repos, la maladie de Parkinson, le parkinsonisme secondaire, la maladie d'Huntington, le syndrome de type Parkinson, PSP, MSA, ALS, le syndrome de Shy-Drager et des troubles résultant conditions d'une lésion cérébrale notamment une intoxication par le monoxyde de carbone ou le manganèse.

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