Compositions for diagnosis of dental caries activity

G - Physics – 01 – N

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G01N 33/48 (2006.01) C12Q 1/04 (2006.01) G01N 33/52 (2006.01)

Patent

CA 1161345

ABSTRACT OF THE DISCLOSURE Compositions capable of evaluating the activity of dental caries using color reaction, which comprise an aqueous solution containing coloring agents and water-soluble subs- tances capable of producing an osmotic pressure higher than physiological pressure on the cell membrane of cariogenic bacteria but are free from any buffer action by themselves. Upon introducing dental plaque of a dental caries of a patient into this solution and measuring the activity of the sordes by means of color reaction, it is possible to readily evaluate the actual state of dental caries and its activity without any cul- tivation of cariogenic bacterial being required.

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