Compositions for improving lipid metabolism

Details Compositions for improving lipid metabolism Compositions for improving lipid metabolism

A - Human Necessities

61

K

A61K 38/40 (2006.01) A61K 9/14 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01) A61K 38/01 (2006.01) A61K 38/16 (2006.01) A61P 1/16 (2006.01) A61P 3/04 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) A61P 9/12 (2006.01)

Patent

CA 2471766

It is intended to provide medicinal compositions which contain as the active ingredient at least one member selected from the group consisting of lactoferrin proteins including lactoferrin and conalbumin and enzymatically digested products of lactoferrin proteins including lactoferricin and peptides of conalbumin corresponding to lactoferricin. These compositions are usable as lipid metabolism improving agents. Moreover, they are useful in treating lifestyle-related diseases such as hypercholesterolemia, hypertriglycedemia, low-density lipoprotein hypercholesterolemia, high-density lipoprotein hypocholesterolemia, obesity, fat liver, cholesterol cholelithiasis, severe obesity, hyperlipemia, hypertension, type II diabetes and so on. These composition can elevate basal metabolic rate.

L'invention concerne des compositions médicinales qui contiennent, comme principe actif, au moins un constituant sélectionné dans le groupe constitué par des protéines lactoferrines comprenant la lactoferrine et la conalbumine, et par des produits des protéines lactoferrines digérés par action enzymatique comprenant la lactoferricine et des peptides de conalbumine correspondants à la lactoferricine. Ces compositions peuvent être utilisées comme agents améliorants du métabolisme lipidique. De plus, elles sont utiles dans le traitement de maladies liées au mode de vie, telles que l'hypercholestérolémie, l'hypertriglycéridémie, l'hypercholestérolémie à lipoprotéines de basse densité, l'hypercholestérolémie à lipoprotéines de haute densité, l'obésité, le foie gras, la cholélithiase induite par le cholestérol, l'obésité grave, l'hyperlipidémie, l'hypertension, le diabète non insulino-dépendant, etc Ces compositions peuvent élever le taux de métabolisme basal.

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