Compositions for intranasal administration

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/00 (2006.01) A61K 9/14 (2006.01)

Patent

CA 2583794

The present invention relates to pharmaceutical compositions for administration to the nasal tract. In particular, the invention relates to dry powder compositions comprising cellulose, and in particular hyroxypropylmethylcellulose (HPMC), and one or more therapeutic agents. It has been shown that administration of HPMC to the nasal cavity is capable of enhancing natural mucus. These powders, and the gel that forms when they are administered to the nasal tract, have now surprisingly been found to be a very effective way of intranasally administering therapeutic agents, and in particular, herbal or homeopathic agents.

L'invention porte sur des compositions pharmaceutiques à administrer par voie nasale. Plus précisément, l'invention porte sur des compositions de poudre sèche contenant de la cellulose, notamment hyroxypropylmethylcellulose (HPMC), et un ou plusieurs agents thérapeutiques. Il a été prouvé que l'administration d'HPMC dans la cavité nasale permet d'améliorer la mucosité naturelle. Ces poudres, et le gel qui se forme lors de l'administration par voie nasale, se sont étonnement révélés être une manière très efficace d'administration intranasale d'agents thérapeutiques, notamment, d'agents médicinaux et homéopathiques.

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