Compositions for linking dna-binding domains and cleavage...

Details Compositions for linking dna-binding domains and cleavage... Compositions for linking dna-binding domains and cleavage...

C - Chemistry, Metallurgy

12

N

C12N 15/09 (2006.01) C12N 9/22 (2006.01)

Patent

CA 2725773

Disclosed herein are compositions for linking DNA binding domains and cleavage domains (or cleavage half-domains) to form non-naturally occurring nucleases. Also described are methods of making and using compositions comprising these linkers.

L'invention concerne des compositions pour relier des domaines liant l'ADN et des domaines de clivage (ou des demi-domaines de clivage) afin de former des nucléases artificielles. Elle concerne également des procédés de préparation et d'utilisation de compositions comprenant ces lieurs.

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