A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/00 (2006.01) A61K 31/00 (2006.01) A61K 47/36 (2006.01)
Patent
CA 2553381
Compositions, and methods of using such compositions, useful for injection into the posterior segments of human or animal eyes are provided. Such compositions include small particles of a poorly soluble therapeutic agent that facilitates formation of concentrated regions of the therapeutic agent in the retinal pigmented epithelium of an eye. The particles are formed by combining a therapeutic agent with an ophthalmically acceptable polymer component. The particles have sizes less than about 3000 nanometers, and in some cases, less than about 200 nanometers. One example of a composition includes particles of triamcinolone acetonide and hyaluronic acid have a size less than about 3000 nanometers.
La présente invention concerne des compositions et des procédés pour l'utilisation de ces compositions convenant pour l'injection dans les parties postérieure de l'oeil des animaux, humains compris. Ces compositions comportent de petites particules d'un agent thérapeutique difficilement soluble, qui facilite la formation de régions à concentrations élevées de l'agent thérapeutique dans l'épithélium pigmentaire rétinien de l'oeil. Ces particules résultent de la combinaison d'un agent thérapeutique avec un composant polymère ophtalmiquement admis. Le calibre de ces particules n'excède pas les 3000 nm, et dans certains cas les 200 nm. L'une de ces compostions contient des particules de triamcinolone acétonide et d'acide hyaluronique n'excédant par un calibre d'environ 3000 nm.
Burke James A.
Hughes Patrick M.
Olejnik Orest
Whitcup Scott M.
Allergan Inc.
Gowling Lafleur Henderson Llp
LandOfFree
Compositions for localized therapy of the eye, comprising... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Compositions for localized therapy of the eye, comprising..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions for localized therapy of the eye, comprising... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1471122