C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/0775 (2010.01) A61K 35/12 (2006.01) C12N 5/02 (2006.01)
Patent
CA 2731821
The present invention relates to inter alia, methods for the generation and maintenance of Mesoderm-derived ISL 1+ Multipotent Progenitors (IMPs), the production of a number of pluripotent cells including and epicardial pluripotent cells (EPCs) and using these cells to produce endothelial cells, cardiomyocytes, smooth muscle cells, vascular cells and other cells and related methods as otherwise disclosed herein. The invention also relates to compositions comprising a population of cells.
La présente invention porte, entre autres, sur des procédés pour la génération et l'entretien de progéniteurs multipotents ISL1+ issus du mésoderme (IMP), la production d'un nombre de cellules pluripotentes comprenant des cellules pluripotentes épicardiques (EPCS), et l'utilisation de ces cellules pour produire des cellules endothéliales, des cardiomyocytes, des cellules de muscle lisse, des cellules vasculaires et autres cellules, et sur des procédés apparentés tels qu'autrement décrits ici. L'invention porte également sur des compositions comprenant une population de cellules.
Dalton Stephen
Reynolds David
Cassan Maclean
The University Of Georgia Research Foundation Inc.
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