Compositions for mucosal and oral administration comprising...

A - Human Necessities – 61 – K

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A61K 38/06 (2006.01) A61K 38/07 (2006.01) A61K 38/24 (2006.01) A61P 3/10 (2006.01) A61P 19/02 (2006.01) A61P 29/00 (2006.01) A61P 37/00 (2006.01) A61P 37/06 (2006.01)

Patent

CA 2520655

The invention relates to the field of immunology, more specifically to the field of immune-mediated disorders such as allergies, auto-immune disease, transplantationrelated disease and other inflammatory diseases. The invention in particular relates to the systemic treatment of inflammatory disease by oral or mucosal administration of a pharmaceutical composition with a gene- regulatory peptide. The invention provides a pharmaceutical composition in a form for mucosal application for the treatment of a subject suffering from disease, said pharmaceutical composition comprising a pharmacologically effective amount of a gene-regulatory peptide or a functional analogue thereof together with a pharmaceutically acceptable diluent.

L'invention à trait au domaine de l'immunologie et notamment au domaine des troubles liés à l'immunité, tels que les allergies, les maladies auto-immunes, les maladies liées aux transplantations et autres maladies inflammatoires. Elle porte en particulier sur le traitement systémique des maladies inflammatoires par administration par voie buccale ou mucosale d'une préparation pharmaceutique contenant un peptide de régulation génique. Elle porte en outre sur une préparation pharmaceutique s'appliquant sur les muqueuses et comprenant une quantité efficace d'un peptide de régulation génique ou d'un de ses analogues fonctionnels, ainsi qu'un diluant pharmacocompatible.

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