Compositions for proliferation of cells and related methods

Details Compositions for proliferation of cells and related methods Compositions for proliferation of cells and related methods

C - Chemistry, Metallurgy

12

N

C12N 5/071 (2010.01) A61K 8/64 (2006.01) A61K 8/72 (2006.01) A61K 31/7088 (2006.01) A61K 35/12 (2006.01) A61K 39/395 (2006.01) C12Q 1/02 (2006.01)

Patent

CA 2738496

We have discovered that p63 inhibition results in increased cellular proliferation. We have also performed a screen for agents capable of increasing cellular proliferation, (e.g., of stem cells such as skin-derived precursors (SKPs)). The invention therefore invention provides compositions, methods, and kits for increasing proliferation of cells, using compounds that decrease p63 expression or activity or using the compounds described herein. The invention also features methods of using these compounds for increasing hair growth, improving skin health, or promoting skin repair in a subject.

Selon la présente invention, nous avons découvert que linhibition de p63 conduit à une prolifération cellulaire augmentée. Nous avons également effectué un criblage dagents capables daugmenter la prolifération cellulaire (par exemple, de cellules souches telles que des précurseurs dérivés de la peau (SKP)). Par conséquent, linvention concerne des compositions, des procédés, et des kits pour augmenter la prolifération de cellules, en utilisant des composés qui diminuent lexpression ou lactivité de p63 ou lutilisation des composés présentement décrits. Linvention concerne en outre des procédés dutilisation de ces composés pour augmenter la croissance des cheveux, améliorer la santé de la peau, ou favoriser la réparation de la peau chez un sujet.

Affiliated with

Also associated with

Rating

Compositions for proliferation of cells and related methods does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compositions for proliferation of cells and related methods, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions for proliferation of cells and related methods will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1649884