Compositions for pulmonary delivery

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/72 (2006.01) A61K 39/395 (2006.01) A61P 11/00 (2006.01) C07K 1/02 (2006.01) C07K 16/00 (2006.01)

Patent

CA 2707986

The present invention relates to methods of direct pulmonary delivery of polypeptides e.g. of domain antibodies, and to particular polypeptide compositions suitable for direct pulmonary delivery. The invention also relates to use of such compositions in medicine, e.g. for the treatment and diagnosis of lung disease, for example for treating Chronic Obstructive Pulmonary Disease (COPD) and asthma.

La présente invention concerne des procédés permettant une administration pulmonaire directe de polypeptides, notamment d'anticorps à domaine, ainsi que des compositions polypeptidiques particulières appropriées à une administration pulmonaire directe. L'invention concerne également l'utilisation de telles compositions dans le domaine médical, par exemple pour le traitement et le diagnostic de maladies pulmonaires, notamment le traitement de la bronchopneumopathie chronique obstructive (BPCO) et de l'asthme.

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