Compositions for the prevention and treatment of neuroinjury...

A - Human Necessities – 61 – K

Patent

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A61K 38/18 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2708674

A method for preventing or ameliorating secondary neuronal injury and inflammation following traumatic brain injury (TBI) is disclosed. The method comprises the step of administering into a subject in need of such treatment an effective amount of a pharmaceutical composition containing a neuregulin (NRG), a variant of NRG, or an expression vector encoding a NRG or a variant of NRG.

L'invention concerne une méthode pour prévenir ou traiter une lésion neurologique secondaire et une inflammation consécutives à une lésion cérébrale traumatique cérébral. Cette méthode consiste à administrer à un patient nécessitant un tel traitement une quantité efficace d'une composition pharmaceutique contenant une neuréguline (NRG), un variant de NRG ou un vecteur d'expression codant pour une NRG ou un variant de NRG.

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