Compositions for the treatment of hepatitis c and methods...

A - Human Necessities – 61 – K

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A61K 31/55 (2006.01) A61P 31/14 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2664935

The present invention pertains to a composition comprising Ibogaine, an indole alkaloid, its active salts and its principal metabolite noribogaine, a demethylated form of ibogaine, for the treatment of hepatitis C and hepatitis C related complications, administered in single or multiple dose regimens effective to reduce somatic complaints, liver enzyme values and viral load caused by chronic hepatitis C in patients, and methods of using the same.

La présente invention concerne une composition qui comprend un indole alcaloïde, l'ibogaïne, ses sels actifs et son principal métabolite, la noribogaïne, forme dé-méthylée de l'ibogaïne, et qui est destinée au traitement de l'hépatite C et des complications liées à l'hépatite C lorsqu'elle est administrée dans des schémas à dose unique ou multiple efficaces pour réduire les symptômes somatiques, les valeurs des enzymes hépatiques et la charge virale causée par l'hépatite C chronique chez les patients. L'invention concerne également des procédés d'utilisation de ladite composition.

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