A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/40 (2006.01) C07K 16/12 (2006.01)
Patent
CA 2507338
The invention relates to the field of immunology and, more specifically, to the treatment of infectious diseases caused by mycobacteria, whereby antibody compositions are administered mucosally and in other ways for the prophylactic and therapeutic treatment of said diseases. The invention relates to the preparation of compositions of human antibodies of class IgG, secretory IgA or mixtures of both having a specific activity against mycobacterial antigens for the prevention and treatment of infections caused by said type of micro- organism. The inventive compositions have demonstrated their ability to prevent in vivo mycobacterial infection.
La présente invention concerne le domaine de l'immunologie et plus précisément une méthode destinée au traitement de maladies infectieuses causées par des mycobactéries. Cette méthode consiste à administrer, par voie muqueuse et d'autres voies, des compositions à base d'anticorps à effet préventif et thérapeutique. La présente invention concerne la préparation de compositions à base d'anticorps humains de type IgG et/ou IgA sécrétoires, présentant une activité spécifique contre les antigènes mycobactériens, pour la prévention et le traitement d'infections causées par ce type de micro-organisme. Ces compositions permettent d'inhiber une infection mycobactérienne in vivo.
Acosta Dominguez Armando
Cadiz Lahenz Armando
Falero Diaz Gustavo
Gonzalez Victoriano Gustavo Sierra
Infante Bourzac Juan Francisco
Instituto Finlay. Centro de Investigacion Produccion de Vacunas
Macrae & Co.
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