Compositions for the treatment of parasitic and fungal...

Details Compositions for the treatment of parasitic and fungal... Compositions for the treatment of parasitic and fungal...

A - Human Necessities

61

K

A61K 31/70 (2006.01) A01N 43/90 (2006.01) A23L 3/3562 (2006.01) A61K 31/17 (2006.01) A61K 31/34 (2006.01) A61K 31/415 (2006.01) A61K 31/44 (2006.01) A61K 31/505 (2006.01) A61K 31/52 (2006.01) A61K 33/24 (2006.01) A61K 35/12 (2006.01) A61K 35/14 (2006.01) A61K 35/16 (2006.01) A61K 35/28 (2006.01) A61K 45/00 (2006.01) A61P 31/00 (2006.01) C07H 19/167 (2006.01) C12N 9/99 (2006.01)

Patent

CA 2206511

This invention relates to compositions comprising an adenosine derivative and a deaminase inhibitor for the prevention and treatment of fungal and fungal-like infections and parasitic infections by eukaryotic organisms. Parasitic infections which are treatable and preventable with these compositions include malaria, trypanosmiasis,leishmania,toxoplasmosis,sarcocystis,pneumocystis,schistosomiasis, blood flukes and elephantitis. Other infections which are treatable and preventable with these compositions are responsible for fungal diseases such as candidiasis, cryptococcosis, blastomycosis, aspergillosis, paracoccidiodomycosis and coccidioidomycosis, and the fungal-like diseases nocardiosis and actinomycosis. The invention also relates to methods for utilizing these compositions in treatment regiments. Treatments may be either in vivo or in vitro. In vivo treatments involve administration of compositions of the invention to mammals suspected or at risk of being infected with a parasitic or fungal organism. In vitro treatments involve incubation of cells, tissues, biological products derived from living materials or foods with compositions of the invention to inhibit or prevent further infection. The invention also relates to the treatment or prevention of neoplastic disorders.

Cette invention porte sur des compositions contenant un dérivé de l'adénosine et un inhibiteur de la déaminase pour la prévention et le traitement des infections fongiques et autres infections apparentées et des infections parasitaires causées par des eucaryotes. Les infections parasitaires qui peuvent être traitées et prévenues avec ces compositions sont le paludisme, la trypanosomiase, la leishmaniose, la toxoplasmose, la sarcocystose, les infections à pneumocystis, la bilharziose, la distomatose et l'éléphantiasis. Au nombre des autres infections qu'on peut prévenir et traiter avec ces compositions, mentionnons les infections fongiques comme la candidose, la cryptococcose, la blastomycose, l'aspergillose, la paracoccidiodomycose et la coccidioidomycose et les infections apparentées comme la nocardiose et l'actinomycose. L'invention a également trait à des méthodes d'utilisation de ces compositions dans les régimes thérapeutiques. Les traitements peuvent s'effectuer in vitro ou in vivo. Les traitements in vivo consistent en l'administration des compositions de cette invention aux mammifères qu'on soupçonne ou qui risquent d'être infectés par des parasites ou des mycètes. Les traitements in vitro consistent en l'incubation de cellules, de tissus et de produits biologiques dérivés de la matière vivante ou d'aliments avec les compositions de l'invention afin d'inhiber ou de prévenir l'infection. L'invention porte également sur le traitement et la prévention des néoplasies.

Affiliated with

Also associated with

Rating

Compositions for the treatment of parasitic and fungal... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compositions for the treatment of parasitic and fungal..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions for the treatment of parasitic and fungal... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1913075