C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 7/04 (2006.01) A61K 38/08 (2006.01) C07K 7/06 (2006.01) C07K 14/72 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2396739
The present invention relates to a composition of matter comprising novel prostaglandin E2 receptor antagonists, and their use in treatments for regulating the fluid filtration in the kidney, preventing bone mineral loss in osteoporosis and dental disease and additionally, closure of ductus arteriosus (DA) in premature infants or fetal animals. Additionally, the compositions include linear peptides, peptide analogs, and peptidomimetics.
L'invention concerne une composition comprenant des antagonistes du récepteur E2 de prostaglandine, et ses utilisations dans des traitements destinés à réguler la filtration de liquides dans le rein, à empêcher une perte minérale osseuse dans l'ostéoporose et des affections dentaires et, en outre, la fermeture du canal artériel chez des prématurés et des animaux foetaux. Les compositions contiennent, en outre, des peptides linéaires, des analogues de peptides ainsi que des peptidomimétiques.
Chemtob Sylvain
Peri Krishna G.
Goudreau Gage Dubuc
Hopital Sainte-Justine
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