A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/00 (2006.01) A61K 31/40 (2006.01) A61K 31/435 (2006.01) A61K 31/445 (2006.01) A61K 31/70 (2006.01) A61K 45/06 (2006.01)
Patent
CA 2293415
The invention concerns the use of direct or indirect selective inhibitors of the Xa factor acting via antithrombin III, on their own or combined with one or several compounds with platelet antiaggregating activity, for preparing medicines for preventing or treating arterial thromboembolism. The invention also concerns pharmaceutical compositions containing one or several direct or indirect selective inhibitors of Xa factor acting via antithrombin III in association with one or several compounds with platelet antiaggregating activity, and, optionally one or several pharmaceutically acceptable carriers.
L'invention concerne l'utilisation d'inhibiteurs sélectifs directs ou indirects du facteur Xa agissant via l'antithrombine III, seuls ou en combinaison avec un ou plusieurs composés à activité antiagrégante plaquettaire, pour la préparation de médicaments destinés à prévenir et à traiter les maladies thromboemboliques artérielles. Font également l'objet de l'invention des compositions pharmaceutiques contenant un ou plusieurs inhibiteurs sélectifs directs ou indirects du facteur Xa agissant via l'antithrombine III en association avec un ou plusieurs composés à activité antiagrégante plaquettaire, et, éventuellement un ou plusieurs véhicules pharmaceutiquement acceptables.
Bernat Andre
Herbert Jean-Marc
Petitou Maurice
Van Amsterdam Ronald
Akzo Nobel Nv
Kirby Eades Gale Baker
Sanofi-Aventis
Sanofi-Synthelabo
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