Compositions for treating ischemia-related neuronal damage

Details Compositions for treating ischemia-related neuronal damage Compositions for treating ischemia-related neuronal damage

C - Chemistry, Metallurgy

07

K

C07K 14/435 (2006.01) A61K 38/17 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2045473

A pharmaceutical composition effective in reducing neuronal damage related to an ischemic condition in a mammalian species. The composition includes a neuronal calcium-channel antagonist compound effective to block norepinephrine release in mammalian CNS neuronal cells, and characterized by specific high affinity binding to an omega-conotoxin MVIIA binding pro- tein. Also disclosed are novel omega-conotoxin peptides.

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