A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/127 (2006.01) A61K 31/355 (2006.01)
Patent
CA 2575906
The present invention relates to compositions containing a) at least one monoacyl lipid; b) at least one diacyl glycerol and/or tochopherol; and c) at least one fragmentation agent; and optionally an active agent. The compositions are capable of self-dispersing to provide colloidal non-lamellar particles upon contact with an aqueous fluid. The invention additionally provides a method for forming non-lamellar particles from such compositions, and pharmaceutical formulations containing the compositions, plus non-lamellar particles formable from the compositions.
La présente invention a trait à des compositions contenant: a) au moins un lipide monoacyle, b) au moins un diacylglycérol et/ou tocophérol, et c) au moins un agent de fragmentation, et éventuellement un agent actif. Les compositions sont capables de dispersion autonome pour fournir des particules colloïdales non lamellaires lors d'un contact avec un fluide aqueux. L'invention a trait en outre à un procédé pour la formation de particules non lamellaires à partir de telles compositions, et à des formulation pharmaceutiques contenant les compositions, ainsi que des particules non lamellaires susceptibles d'être formées à partir des compositions.
Joabsson Fredrik
Johnsson Markus
Tiberg Fredrik
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Camurus Ab
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