Compositions having improved bioavailability of eletriptan

Details Compositions having improved bioavailability of eletriptan Compositions having improved bioavailability of eletriptan

A - Human Necessities

61

K

A61K 31/4045 (2006.01) A61K 31/275 (2006.01) A61K 31/40 (2006.01) A61K 31/404 (2006.01) A61K 45/06 (2006.01) A61P 25/06 (2006.01) A61K 47/10 (2006.01) A61K 47/14 (2006.01) A61K 47/22 (2006.01) A61K 47/44 (2006.01)

Patent

CA 2439917

The bioavailabilty of eletriptan can be increased by co-administering eletriptan with a p-glycoprotein (p-gp) inhibitor. The eletriptan and p-gp inhibitor can be administered together in a composition or as separate components. If administered separately, they can be embodied as a kit.

Selon la présente invention, la biodisponibilité de l'eletriptan peut être accrue au moyen de la co-administration d'eletriptan associée à un inhibiteur de la p-glycoprotéine (p-gp). L'eletriptan et l'inhibiteur de la p-gp peuvent être administrés ensemble dans une composition, ou sous la forme de composants individuels. S'ils sont administrés séparément, ils peuvent être incorporés sous la forme d'une trousse.

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