Compositions having tnf production inhibitory effect and tnf...

A - Human Necessities – 23 – L

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A23L 1/30 (2006.01) A61K 35/78 (2000.01)

Patent

CA 2451078

It is intended to provide compositions having a TNF production inhibitory effect which are free from any troubles in side effects or safety and inhibit the excessive production of TNF, thereby being useful in preventing or ameliorating various diseases mediated by TNF such as chronic inflammatory diseases, acute inflammatory diseases, inflammatory diseases caused by infection, autoimmune diseases and allergic diseases; and TNF production inhibitors. It is found out that cinnamon extract, clove extract, licorice root extract and ginger extract have each a TNF production inhibitory effect. Thus, the above object can be achieved by compositions having a TNF production inhibitory effect and TNF production inhibitors which contain at least one member selected from among cinnamon extract, clove extract, licorice root extract and ginger extract.

La présente invention concerne des compositions ayant pour effet d'inhiber la production du facteur de nécrose tumorale, sans effets secondaires et sûrs à l'utilisation. Ces compositions, qui bloquent toute surproduction des TNF, conviennent particulièrement à la prévention ou l'amélioration de diverses affections à médiation des TNF, et notamment les maladies inflammatoires chroniques, les maladies inflammatoires aiguës, les maladies inflammatoires d'origine infectieuse, les maladies auto-immunes, et les maladies allergiques. L'invention concerne également des inhibiteurs de production des TNF.

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