A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) A61K 31/7088 (2006.01) A61K 41/00 (2006.01) A61K 45/00 (2006.01) A61K 47/12 (2006.01) A61K 47/26 (2006.01) A61K 47/34 (2006.01) A61K 47/42 (2006.01) A61K 47/44 (2006.01) A61P 37/06 (2006.01) A61P 43/00 (2006.01)
Patent
CA 2467915
It is intended to provide a novel and efficacious strategy in organ transplantation. Namely, remedies and methods for preventing acute rejection in organ transplantation and improving the prognostic are provided. A remedy for inhibiting rejection in organ transplantation which contain an NF-.kappa.B decoy compound is provided. The organ transplantation is typified by kidney transplantation. This remedy may further contain an ultrasonic test contrast medium. Also, a remedy for improving the prognostic of organ transplantation is provided. This remedy is administered to the donor organ and thus elevates the transfection efficiency of the NF-.kappa.B decoy compound into the organ by ultrasonication.
Stratégie nouvelle et efficace de transplantation d'organe. L'invention concerne notamment des remèdes et des procédés destinés à empêcher le rejet aigu dans la transplantation d'organe et à améliorer le pronostic. Un remède destiné à inhiber le rejet dans la transplantation d'organe contient un composé leurre NF-kB. La transplantation d'organe caractérisée est la transplantation du rein. Ledit remède peut également contenir un milieu de contraste pour essai ultrasonore. Par ailleurs, un remède conçu pour améliorer le pronostic de la transplantation d'organe est prévu. Ce remède est administré à l'organe donneur et augmente ainsi l'efficacité de transfection du composé leurre NF-kB dans l'organe, par ultrasonication.
Azuma Haruhito
Morishita Ryuichi
Ogihara Toshio
Tomita Naruya
Anges Mg Inc.
Sim & Mcburney
LandOfFree
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