A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/195 (2006.01) A61K 31/23 (2006.01) A61K 31/575 (2006.01) A61K 45/06 (2006.01) A61P 9/00 (2006.01)
Patent
CA 2395446
The present invention is directed to compositions comprising: (a) a first component selected from the group consisting of L-arginine, polypeptides thereof, acceptable salts thereof, pro-forms thereof, and mixtures thereof; and (b) a second component selected from the group consisting of sterols, stanols, esters thereof, polyol fatty acid polyesters, and mixtures thereof. The present invention is further directed to kits comprising these compositions as well as methods of using the compositions. The compositions, kits, and methods herein are useful for providing general health benefits to the consumer, particularly cardiovascular benefits, anti-menopausal benefits and/or treating sexual dysfunction (particularly, erectile dysfunction). Most particularly, the compositions, kits, and methods herein are useful for providing cardiovascular benefits, including lowering cholesterol in the consumer, treating, preventing, and/or inhibiting heart disease (e.g., atherosclerosis, restenosis, thrombosis) and, for example, treating other conditions such as hypercholesterolemia, hypertension, poor circulation, and complications associated with diabetes.
La présente invention concerne des compositions comprenant (a) un premier composant appartenant au groupe constitué de la L-arginine et de certains de ses polypeptides, de ses sels acceptables, de ses pro-formes, et de certains leurs mélanges, et (b) un second composant appartenant au groupe constitué des stérols, stanols, leurs esters, des polyesters d'acide gras polyoliques, et certains de leurs mélanges. L'invention concerne également des nécessaires comprenant ces compositions ainsi que des procédés pour l'utilisation de ces compositions. Ces compositions, nécessaires et procédés procurent au consommateur une amélioration de l'état de santé générale, notamment des améliorations cardio-vasculaires, des améliorations anti-ménopausales, et/ou de traiter des troubles sexuels tels que ceux de l'érection. Plus particulièrement, ces compositions, nécessaires et procédés apportent des améliorations cardio-vasculaires, notamment l'abaissement de la cholestérolémie chez le consommateur, le traitement, la prévention et/ou l'inhibition d'affections cardiaques telles que l'athérosclérose, la resténose, la thrombose, et permettent de traiter d'autres états tels que l'hypercholestérolémie, l'hypertension, la mauvaise circulation, et des complications liées au diabète.
Niehoff Raymond Louis
Sarama Robert Joseph
Dimock Stratton Llp
The Procter & Gamble Company
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